My current appointments and place of work
A sequenced strategy for improving outcomes in people with knee osteoarthritis pain (SKOAP)
Knee osteoarthritis is one of the leading causes of chronic pain and disability worldwide, affecting over 30% of older adults. It represents a major global health and economic burden to individuals and society.
The overarching goal of this multi-site study is to conduct a sequential parallel group randomized controlled trial (RCT) to evaluate the comparative effectiveness of conservative behavioral and non-opioid pharmacological treatments (Phase 1) and, among those that indicate interest in obtaining further treatment and those inappropriate for conservative treatment, the benefits of procedural interventions (Phase 2).
This study will also evaluate whether clinical and psychosocial phenotypes predict short- and longer-term treatment response. This way, it will provide meaningful information regarding effectiveness of treatments across key subgroups of patients.
Principal investigators:
Steven P. Cohen, Claudia M. Campbell and Renan Castillo
Johns Hopkins University, Baltimore, MD