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About my blogs
About my blogs
I discuss topics related to pain management in an accessible way for anyone who wants to know more about this fascinating and poorly understood area of medicine, including healthcare professionals, patients, and students.
My purpose is solely educational and non-profit. While I aim to make the best use of the available scientific evidence, the content of my blogs primarily reflects my personal opinion.
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Epidural steroids: Long-term improvement, but ...
Epidural steroid injections in older adults: study with 2-years follow-up shows that patients improve, but unlikely due to the injection.

Michele Curatolo
Jul 20, 20224 min read
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Acute back pain after osteoporotic fractures: Which medication?
Acute back pain after osteoporotic vertebral fractures is a public health issue. Choosing a medication that limits harm is challenging.

Michele Curatolo
Jul 6, 20222 min read
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Neck pain and headache: Can stem from the C1-2 joint
Pain at the upper neck and headache can stem from the C1-2 joint. Steroid injection or surgery can be effective

Michele Curatolo
Jun 22, 20222 min read
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Explaining "pain sensitization" to patients
Sensitization of neural pathways is a crucial determinant of chronic pain, and has treatment consequences. How to explain this to patients?

Michele Curatolo
Jun 8, 20223 min read
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The huge gap between discoveries and availability of effective pain medications
A new research pathway is proposed to translate discoveries of pharmacological targets into effective treatments of pain.

Michele Curatolo
May 25, 20223 min read
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Prognostic nerve blocks: meaningful or meaningless?
Prognostic nerve blocks to predict the effect of a subsequent treatment may be meaningful or not, depending on the nature of the procedure.

Michele Curatolo
May 12, 20224 min read
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Improve your sleep, mood and physical function, and you may have less pain
In chronic pain, improvement in sleep, psychological and physical functioning may precede reduction in pain.

Michele Curatolo
Apr 27, 20222 min read
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Adding a procedure to current treatment of chronic pain
A recent study used a pragmatic approach to demonstrate that adding a hip injection to current treatment improves pain for 6 months.

Michele Curatolo
Apr 13, 20223 min read
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Exercise for chronic pain: when patients and health care professionals are not on the same page
Many patients with chronic pain decline therapeutic exercise because it increases pain. Is pain relief the right treatment goal?

Michele Curatolo
Apr 6, 20223 min read
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The confusion around "diagnostic" nerve blocks for chronic pain
A patient becomes pain-free after anesthetizing a nerve: does it tell us where the pain comes from?

Michele Curatolo
Mar 23, 20224 min read
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Better nutrition, less pain: Turn your pantry into a potent tool for better health and less pain
"You change your body chemistry each time you eat". Evidence for associations between diet and pain are growing.
Heather Tick
Mar 15, 20224 min read
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Therapeutic nerve blocks for chronic pain: An unexplored potential
Placebo-controlled studies are unsuited to study therapeutic nerve blocks for chronic pain. More feasible research models are available.

Michele Curatolo
Mar 4, 20224 min read
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What does local tenderness say about the origin of pain?
Tenderness evoked by pressure is typically interpreted as a sign of injury causing pain. However, it is of very limited diagnostic value.

Michele Curatolo
Feb 23, 20223 min read
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Pain from multiple body areas: when arithmetics doesn't work
Pain from multiple body sites is frequently highly disabling. 1+1+1 is more than 3. Why, and what can we do?

Michele Curatolo
Feb 9, 20222 min read
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How blood and urine metabolites could help understand chronic pain
We need to understand better chronic pain at individual level. The study of metabolites (metabolomics) is a promising perspective.

Michele Curatolo
Feb 2, 20223 min read
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Why we shouldn't care much about x-ray and MRI for back pain
X-ray and MRI for back pain are over-valued. Frequently, they do not contribute to the diagnosis and may mislead treatment.

Michele Curatolo
Jan 26, 20223 min read
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Is psychosocial distress a contraindication to pain procedures?
The challenges of considering procedures for chronic pain in patients with psychosocial distress.

Michele Curatolo
Jan 19, 20223 min read
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Is "chronic pain" a diagnosis? Yes and no.
We need to translate the complexity and heterogeneity of chronic pain into meaningful diagnoses.

Michele Curatolo
Jan 11, 20223 min read
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Why would an anesthetic nerve injection produce long-term pain relief?
Local anesthetics have a short duration of action, so why would they work in chronic pain?

Michele Curatolo
Jan 5, 20224 min read
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Opioid escalation after surgery in patients with opioid use disorder
Definition According to the American Psychiatric Association, opioid use disorder is a condition in which there is uncontrolled use of...

Michele Curatolo
Dec 29, 20213 min read
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